ChiLTERN Milestones

ChiLTERN milestones are scheduled dates marking the achievement of a deliverable or associated activity. There is no written document for ChiLTERN milestones just dates entered on to the EC Participant Portal by the scheduled deadline ().


  • MS1 Project Manual (4) UoB – dated on EC Portal
  • MS2 Project Data Management Plan (6) UoB  – dated on EC Portal
  • MS3 Protocol Finalisation (9) UoB  – dated on EC Portal
  • MS4 UK ethics and regulatory approval (12) UoB  – dated on EC Portal
  • MS5 Ethics and regulatoryapproval in 50% of NCCs (18) UoB
  • MS6 150 (50%) patients recruited (42) UoB
  • MS7 300 (100%) patients recruited (60) UoB
  • MS8 Development of an European biorepository (60) IGTP
  • MS9 Establishment of central pathological review (60) IGTP
  • MS10 Generation of a list of best diagnostic/prognostic biomarkers (pathological & molecular) (60) IGTP
  • MS11 Validation of the list of diagnostic/prognostic biomarkers in specimens obtained at the time of diagnosis (including those of very aggressive tumours) (60) IGTP
  • MS12 Definition of the similarities and differences between childhood and adulthood HCC (60) IGTP
  • MS13 First Validation of CHIC-HS (36) LMU
  • MS14 Validation of CHIC-HS within PHITT (60) LMU
  • MS15 New clinical biological and pathological risk stratification (60) LMU
  • MS16 Development of a European surgical expert platform (60) EKUT
  • MS17 Establishment of central surgical review (60) EKUT
  • MS18 Generation of a list of factors (60) EKUT
  • MS19 Validation of the list of factors defining surgical approaches based on imaging data (60) EKUT
  • MS20 Protocol for PK sample analysis finalised (12) UNEW  – dated on EC Portal
  • MS21 First sample received for PK analysis (15) UNEW  – dated on EC Portal
  • MS22 First sample received for PD analysis (15) UNEW –  – dated on EC Portal
  • MS23 Final WP7 report detailing PK and PD analysis (60) UNEW