We study how the immune system attacks invading pathogens – and why it sometimes goes wrong. We’re particularly interested in microbes that evade or hijack the human immune system. You can learn more about our ERC-funded project to discover more about pathogen evolution on our MitoFun page.
On the right, the fatal fungus Cryptococcus neoformans is escaping from a macrophage (a type of white blood cell) by a process called vomocytosis. Below, you can see the macrophages response – ‘actin flashes’ that act to trap the fungus inside the immune cell.