Hilaire Cheung’s Profile

I have a Master of Philosophy at the University of Hong Kong, and a Bachelor of Science degree at the same university, double major in Chemistry and Biochemistry. My Master Thesis focused on the development of an immunoassay that uses mass spectrometry and metal nanoparticles for indirect protein detection, and use of the mass spectrometry-based proteomics approach to study the effect of arsenic trioxide on leukaemia cells.  Throughout my three-years research career, I have accumulated extensive experiences in mass spectrometry, analytical method development and various biochemical techniques.

The TAPAS EJD-ITN has provided me with a wonderful opportunity to combine my research interests with the opportunity to travel. During the first year of my joint-PhD degree, I will be at the Leibniz Institute for Analytical Sciences, under the supervision of Prof. A. Sickmann and Dr. R. Ahrends. For the second year, I will be based in the Institute of Cardiovascular Sciences, University of Birmingham, UK, under the supervision of Prof. S.P. Watson and Dr. N. Poulter. For the third year, I will be based in Netherlands at the Maastricht University under the supervision of Prof. J.W.M. Heemskerk and Dr. R. Cavill. In the course of the first year and last year, I will be doing a secondment at ALACRIS, Germany.

The aim of my TAPAS project is to develop innovative, predictive models of thrombosis and haemostasis. For that reason, I will focus on GPVI, a membrane receptor protein which is critically involved in platelets activation, and I will be using a combination of multi-omics, advanced microscopy, vessel-on-a-chip model and various biochemical techniques to answer the question.