{"id":135,"date":"2021-11-05T11:54:09","date_gmt":"2021-11-05T11:54:09","guid":{"rendered":"https:\/\/more.bham.ac.uk\/mrc-aim\/?page_id=135"},"modified":"2021-11-16T15:40:41","modified_gmt":"2021-11-16T15:40:41","slug":"research-projects","status":"publish","type":"page","link":"https:\/\/more.bham.ac.uk\/mrc-aim\/research-projects\/","title":{"rendered":"Research Projects"},"content":{"rendered":"\n<p>Below is a sample of current research projects that DTP students are undertaking which demonstrate the breadth of research taking place across the three institutions and associate partners.<\/p>\n\n\n<div class=\"gb-container gb-container-3cee34dc\"><div class=\"gb-inside-container\">\n\n<ul class=\"wp-block-list\" id=\"block-f6430753-d943-4099-af57-4dcf08a763ce\"><li>Development of an intradermal or inhaled DNA vaccine for COVID-19 and beyond<\/li><li>Translation of novel polymer anti-bacterial coating to invasive medical devices used in the neonatal intensive care for high risk preterm infants<\/li><li>Characterising cortical network dysfunction in schizophrenia in human neurons derived from induced pluripotent stem cells<\/li><li>Investigating the role played by inflammation in the development of colorectal cancer<\/li><li>Modelling Basal-Ganglia contributions to motivational impairments in Parkinson\u2019s Disease<\/li><li>Structure-function analysis of CUL2LRR1 ubiquitin ligase<\/li><li>Multi-system effects of Very Low Calorie Dietary (VLCD) in type two diabetes (T2d) in TWO different populations<\/li><li>Implementation of the patient-derived explant (PDE) platform for evaluating tumour responses to novel immunotherapies<\/li><li>Converting insult into injury: Cellular and structural biology studies of a macromolecular complex that links inflammation with scarring in fibrotic disease<\/li><li>Multimerisation of ELAV\/Hu proteins \u2013 a key mechanism ensuring specificity for RNA recognition in health and disease&nbsp;<\/li><li>The molecular basis for action of allosteric ligands in chemokine receptors<\/li><li>Understanding how tetraspains and the \u2018molecular scissor\u2019 ADAM10 promote blood cancer<\/li><li>Sol to scaffold: novel hybrid formulations for 3D biofabrication of in vitro tissue models<\/li><li>Structural Refinement of teixobactin for treating complex Propionibacterium acnes infection<\/li><li>Understanding the genetic basis of disease endotypes in idiopathic pulmonary fibrosis<\/li><li>Creating an AI based data assistant to bridge genotype to metadata &#8211; linking primary clinical data to biobank samples.<\/li><\/ul>\n\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Below is a sample of current research projects that DTP students are undertaking which demonstrate the breadth of research taking place across the three institutions and associate partners. Development of an intradermal or inhaled DNA vaccine for COVID-19 and beyond Translation of novel polymer anti-bacterial coating to invasive medical devices used in the neonatal intensive care for high risk preterm &#8230; <a title=\"Research Projects\" class=\"read-more\" href=\"https:\/\/more.bham.ac.uk\/mrc-aim\/research-projects\/\" aria-label=\"More on Research Projects\">Read More<\/a><\/p>\n","protected":false},"author":113,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-135","page","type-page","status-publish"],"featured_image_urls_v2":{"full":"","thumbnail":"","medium":"","medium_large":"","large":"","1536x1536":"","2048x2048":"","ab-block-post-grid-landscape":"","ab-block-post-grid-square":""},"post_excerpt_stackable_v2":"<p>Below is a sample of current research projects that DTP students are undertaking which demonstrate the breadth of research taking place across the three institutions and associate partners. Development of an intradermal or inhaled DNA vaccine for COVID-19 and beyondTranslation of novel polymer anti-bacterial coating to invasive medical devices used in the neonatal intensive care for high risk preterm infantsCharacterising cortical network dysfunction in schizophrenia in human neurons derived from induced pluripotent stem cellsInvestigating the role played by inflammation in the development of colorectal cancerModelling Basal-Ganglia contributions to motivational impairments in Parkinson\u2019s DiseaseStructure-function analysis of CUL2LRR1 ubiquitin ligaseMulti-system effects of&hellip;<\/p>\n","category_list_v2":"","author_info_v2":{"name":"earlt","url":"https:\/\/more.bham.ac.uk\/mrc-aim\/author\/earlt\/"},"comments_num_v2":"0 comments","featured_image_src":null,"featured_image_src_square":null,"_links":{"self":[{"href":"https:\/\/more.bham.ac.uk\/mrc-aim\/wp-json\/wp\/v2\/pages\/135","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/more.bham.ac.uk\/mrc-aim\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/more.bham.ac.uk\/mrc-aim\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/more.bham.ac.uk\/mrc-aim\/wp-json\/wp\/v2\/users\/113"}],"replies":[{"embeddable":true,"href":"https:\/\/more.bham.ac.uk\/mrc-aim\/wp-json\/wp\/v2\/comments?post=135"}],"version-history":[{"count":10,"href":"https:\/\/more.bham.ac.uk\/mrc-aim\/wp-json\/wp\/v2\/pages\/135\/revisions"}],"predecessor-version":[{"id":255,"href":"https:\/\/more.bham.ac.uk\/mrc-aim\/wp-json\/wp\/v2\/pages\/135\/revisions\/255"}],"wp:attachment":[{"href":"https:\/\/more.bham.ac.uk\/mrc-aim\/wp-json\/wp\/v2\/media?parent=135"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}