{"id":67,"date":"2017-09-21T16:44:35","date_gmt":"2017-09-21T15:44:35","guid":{"rendered":"https:\/\/more.bham.ac.uk\/may\/?page_id=67"},"modified":"2020-07-31T16:29:17","modified_gmt":"2020-07-31T15:29:17","slug":"vomocytosis","status":"publish","type":"page","link":"https:\/\/more.bham.ac.uk\/maylab\/vomocytosis\/","title":{"rendered":"Vomocytosis"},"content":{"rendered":"<p><iframe loading=\"lazy\" title=\"Vomocytosis\" width=\"905\" height=\"509\" src=\"https:\/\/www.youtube.com\/embed\/sqPCor9cirk?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe><\/p>\n<p><span style=\"color: #ffffff\"><span class=\"style_1\">\u2018<a style=\"color: #ffffff\" href=\"https:\/\/en.wikipedia.org\/wiki\/Vomocytosis\">Vomocytosis<\/a>\u2019, the process by which live pathogens are expelled from macrophages<\/span>.\u00a0 A J774 macrophage has internalised c<span class=\"style_2\">ryptococci<\/span> (the round &#8220;balls&#8221;).\u00a0 It tries to kill the fungus by depositing &#8220;killer granules&#8221; known as lysosomes (marked in red) into the phagosome. When the macrophage fails to kill its prey, then the pathogen is suddenly expelled.\u00a0 This expulsion also provides a route for direct transmission of the pathogen to a neighbouring cell (click <a style=\"color: #ffffff\" title=\"http:\/\/www.biomedcentral.com\/1471-2172\/8\/15\" href=\"http:\/\/www.biomedcentral.com\/1471-2172\/8\/15\">here<\/a> for the paper about this process or <a style=\"color: #ffffff\" title=\"http:\/\/www.biomedcentral.com\/1471-2172\/8\/15\/additional\/\" href=\"http:\/\/www.biomedcentral.com\/1471-2172\/8\/15\/additional\/\">here<\/a> to see the movies).<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u2018Vomocytosis\u2019, the process by which live pathogens are expelled from macrophages.\u00a0 A J774 macrophage has internalised cryptococci (the round &#8220;balls&#8221;).\u00a0 It tries to kill the fungus by depositing &#8220;killer granules&#8221; known as lysosomes (marked in red) into the phagosome. When the macrophage fails to kill its prey, then the pathogen is suddenly expelled.\u00a0 This expulsion &hellip;<\/p>\n","protected":false},"author":9,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-67","page","type-page","status-publish","hentry","post","without-featured-image"],"featured_image_urls_v2":{"full":"","thumbnail":"","medium":"","medium_large":"","large":"","1536x1536":"","2048x2048":"","ab-block-post-grid-landscape":"","ab-block-post-grid-square":"","atomic-blocks-featured-image":"","atomic-blocks-featured-image-wide":"","atomic-blocks-logo":""},"post_excerpt_stackable_v2":"<p>\u2018Vomocytosis\u2019, the process by which live pathogens are expelled from macrophages.\u00a0 A J774 macrophage has internalised cryptococci (the round &#8220;balls&#8221;).\u00a0 It tries to kill the fungus by depositing &#8220;killer granules&#8221; known as lysosomes (marked in red) into the phagosome. When the macrophage fails to kill its prey, then the pathogen is suddenly expelled.\u00a0 This expulsion also provides a route for direct transmission of the pathogen to a neighbouring cell (click here for the paper about this process or here to see the movies).<\/p>\n","category_list_v2":"","author_info_v2":{"name":"Simon Levermore","url":"https:\/\/more.bham.ac.uk\/maylab\/author\/levermsj\/"},"comments_num_v2":"0 comments","featured_image_src":null,"featured_image_src_square":null,"_links":{"self":[{"href":"https:\/\/more.bham.ac.uk\/maylab\/wp-json\/wp\/v2\/pages\/67","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/more.bham.ac.uk\/maylab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/more.bham.ac.uk\/maylab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/more.bham.ac.uk\/maylab\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/more.bham.ac.uk\/maylab\/wp-json\/wp\/v2\/comments?post=67"}],"version-history":[{"count":8,"href":"https:\/\/more.bham.ac.uk\/maylab\/wp-json\/wp\/v2\/pages\/67\/revisions"}],"predecessor-version":[{"id":778,"href":"https:\/\/more.bham.ac.uk\/maylab\/wp-json\/wp\/v2\/pages\/67\/revisions\/778"}],"wp:attachment":[{"href":"https:\/\/more.bham.ac.uk\/maylab\/wp-json\/wp\/v2\/media?parent=67"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}